Supply Chain Manager (Sr. Manager or Assoc. Director)

South San Francisco, CA 94080

Posted: 02/28/2019 Employment Type: Direct Hire Industry: Clinical & Scientific Job Number: 15164

Supply Chain Manager (Sr. Manager or Assoc. Director)

South San Francisco, CA


Well-funded biotechnology company, advancing to clinical studies in 2019 with facilities and laboratories in South San Francisco, CA.  We are developing personalized adoptive T cell therapies for the eradication of solid tumors.   We are in the San Francisco bay area, in the heart of the world’ s premier biotechnology research hub.  Offers a competitive compensation and benefits package, including aggressive participation in the growth of the company in the form of stock option grants.  

Developing tumor-mutation targeted T Cells  tailored for each patient. Tumor mutation (neoE) targeting is programmed into the patient’ s own T cells to seek out & kill the tumors. Using (non-viralprecision genome engineering, the neoE-targeted Tcell receptors (TCRs) replace the endogenous TCR of fresh CD8 and CD4 T cells collected from that same patient followed by minimal expansion in closed systems for re-infusion into the patient. These patient-specific neoTCR-P1 cells are formulated to immediately kill all neoantigen-expressing tumors, together with a deep reservoir of ‘ready-to-go’ neoTCR-P1 cells for long term persistence and capable of rapid expansion to prevent future cancer recurrence. 

We are currently recruiting for Supply Chain Manager, Sr. Manager or Associate Director, reporting to the Head of Manufacturing.  This position will be based in South San Francisco.


The  position is responsible for developing and executing the strategic plan for the supply chain functions including the scheduling and inventory planning, purchase and procurement of materials, parts, supplies, and equipment and shipping/receiving.   This role is also responsible for developing, implementing and maintaining supply chain and facilities policies and procedures, developing material schedules, and coordinates these efficiently with purchasing, production, development, research groups and others in the company. 

It is expected that this position will work closely with other corporate functional areas as well as outside vendors to ensure deliverables are met. 
  • Manage the production planning management, inventory control, material management, and shipping/receiving operations
  • Develops and executes the strategy for supply chain function to aggressively reduce the cost of key materials, components and subsystems, reduce material lead times and inventory requirements and associated working capital needs
  • Establishes strategy and plans for sourcing, material supply, production capacity, logistics, and availability to meet forecast.
  • Oversees the management of supply and build planning to include inventory management, master scheduling, forecasting, and logistics of production to meet the global demand plan.
  • Manages Supply chain budgets
  • Establishes performance metrics; tracking, analyzing and reporting performance in terms of quality, safety, cost, and customer satisfaction.
  • Takes corrective action to bring about required change and ensure contract requirements have been executed at a level above the specified standards.
  • Recommends solutions and implements appropriate corrective action for major or complex maintenance issues
  • Ensures that all records for state, federal, and insurance inspections are accurate and up to date.
  • Operates within compliance with FDA and ISO requirements and guidelines.
  • Prepares and reviews contracts, bids, proposals, and vendor agreements for price and acceptability of items.
  • Supervises the negotiation of complex requests for equipment, supplies, and services from suppliers and subcontractors.
  • Provides leadership to organization, hiring and mentoring staff and to ensure all staff are adequately trained
  • Partner with other departments
  • Position may require some travel

 Minimal Qualifications:
  • BS degree with 8 - 10 plus years in a progressive supply chain management with significant experience
  • Demonstrated experience in sourcing techniques to provide cost savings and better materials
  • Strong leadership, communication (both verbal and written) skills
  • Excellent business, financial and negotiating skills are required along with knowledge of quality systems, lean manufacturing processes and project management knowledge
  • Strong working knowledge of MRP and ERP systems
  • Experience implementing world class sourcing tools
  • Knowledge of current requirements for GLP, cGMP, and GCP is also required
  • Direct experience with regulatory submissions
  • Forward-thinking and creative with high ethical standards
  • Team player with leadership skills with ability to influence others to achieve successful regulatory filings and meetings.
  • Well organized and self-directed
  • Strong interpersonal skills with an ability to communicate to people at all levels of an organization


Jesse Ashworth

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