Sr. Research Associate - Gene Editing

South San Francisco, CA 94080

Posted: 12/19/2019 Employment Type: Direct Hire Industry: Clinical & Scientific Job Number: 16900

Job Description

Sr. Research Associate - Gene Editing

South San Francisco, CA



We are in the San Francisco bay area, the heart of the world’ s premier biotechnology research hub.  We are about eradicating cancer, come join our team!

We are currently recruiting for a Sr. Research Associate  who will report to Associate Director and continue advancing cutting edge engineered cell product. This will be a unique opportunity to see your ideas rapidly translate into the clinic and impact patient lives.

The ideal candidate should be experienced the latest molecular cloning and sequencing techniques for the generation and analysis of transgenic T cells. The candidate should enjoy operating in an exceptionally dynamic and cooperative environment and will communicate results to and coordinate efforts with a larger cross-disciplinary team of immunologists, biologists, engineers and bio-informaticians.

  • The candidate will be performing experiments to validate and improve the technology for gene editing (knock-in and knock-out) of endogenous and neoE TCRs, and analyzing the resulting data.
  • She/he must be able to communicate clearly and concisely, both verbally and in the form of written reports. The incumbent will aid in drafting protocols, and provide data for regulatory documentation to support clinical development.

Minimum Qualifications:
  • The ideal candidate will hold a Bachelor’ s degree with 4+ years’ experience, a Master’ s degree with 3+ years’ experience with career focus in cell or molecular biology, biochemistry, or molecular genetics.
  • Industry experience is preferred.
  • The candidate must have hands on experience with nucleic acid purification and use, including primer design, PCR and standard cloning.
  • The candidate should be highly goal-driven and have demonstrated the ability to focus on time-sensitive objectives.

Preferred Qualifications:

An incumbent with experience in the following areas is a plus:
  • Experience with liquid handlers/automation equipment
  • Experience with informatics, data management, or programming
  • Mammalian cell culture and transfection, ideally primary human T cells
  • High-throughput sequencing sample preparation and analysis
  • Site-specific nucleases (e.g. CRISPR and TALENs) and associated cellular and molecular analysis
  • qPCR and/or ddPCR assay design and optimization
  • Flow cytometry or FACS

Meet Your Recruiter

Marissa Kochan

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