Sr. Research Associate, Process Development

Menlo Park, CA 94025

Posted: 08/01/2018 Employment Type: Direct Hire Industry: Clinical & Scientific Job Number: 13605

Our client in Menlo Park is looking to have a Sr. Research Associate, Process Development join their growing team!

Our Company Bio: Bayside Solutions was founded in 2001, Bayside was recognized as one of the fastest growing professional staffing companies in Northern California. The numbers tell the story: We have close to a 100% client retention rate, 700% growth in four plus years and over 95% repeat business. Our dedication to building partnership relationships with both our clients and our recruits is the key to our phenomenal success.

You can find additional information on our company website at www.baysidesolutions.com.

Sr. Research Associate, Process Development

Job Benefits:
  • An opportunity to significantly impart the future of the company’ s operations
  • A competitive base salary
  • On the job training, both in person/online

Summary of Responsibilities:
  • Help with manufacturing of AAV through the downstream purification process (cell lysate to final formulation)
  • Streamline current processes
  • Work hands-on to develop, optimize, and scale-up downstream processes for the purification of AAV vectors from small to large scale purification systems in a laboratory setting
  • Design and execute experiments following appropriate laboratory procedures and produce competent and reproducible results to a high technical standard
  • Appropriately analyze data, interpret results, and maintain accurate records with minimum supervision
  • Interact with Assay Development, QC, QA, and pre-clinical group
  • Develop novel AAV manufacturing processes with the highest quality according to corporate timelines in order to advance Adverum Biotech’ s product pipeline
  • Ensure a safe work place in compliance with the company and EH&S' rules and regulations
  • Keep current with advances in downstream processes for viral vector production

  Required Qualifications:
  • MS with 2-4 years of experience or BS with 4+ years of experience in Chemical Engineering, Biochemistry, Cell & Molecular Biology or related life science fields
  • Gene therapy viral vector production experience is required
  • Expertise in AAV or other gene therapy vector expression in mammalian cells via transient transfection is a plus
  • Hands-on experience with density-gradient ultracentrifugation is highly desirable
  • Experience with protein purification including hands on experience with TFF (Hollow Fiber / Cassettes) UF/DF, GE AKTA (Avant, Pilot), chromatography at small/pilot/large scale is a plus
  • Proficiency in general molecular biology techniques including ELISA, qPCR, BCA
  • Western Blot and Silver Stain experience is preferred but not required
  • Experience drafting SOPs, Batch records, reports, and protocols is preferred

 

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