Senior Scientific Researcher
475 E Grand Ave., SSF42 South San Francisco, CA 94080
Bayside Solutions is seeking a Senior Scientific Researcher to be part of our client’ s team in South San Francisco. This is an opportunity to work with the largest privately held pharmaceutical corporation in the world and ranks among the world' s 20 leading pharmaceutical corporations.
Our Client’ s culture is highly collaborative, offers an environment that encourages employees to expand their knowledge in order to make a profound impact on patients’ lives. This could explain why their company has been recognized as one of the “ Top Twenty Employers” in biotechnology and pharmaceuticals by Science Careers.
Our Company Bio: Bayside Solutions was founded in 2001, Bayside was recognized as one of the fastest growing professional staffing companies in Northern California. The numbers tell the story: We have close to a 100% client retention rate, 700% growth in four plus years and over 95% repeat business. Our dedication to building partnership relationships with both our clients and our recruits is the key to our phenomenal success.
You can find additional information on our company website at www.baysidesolutions.com.
Senior Scientific Researcher
- An opportunity to join a patient-focused organization that is driven to develop, manufacture and commercialize medicines to treat life threatening conditions.
- Work for a company that is local to the bay area and recognized as a leader of innovation.
- Competitive compensation commensurate with experience.
- This position is eligible for medical, vision, dental benefits, paid sick time, and 401K.
Summary of Responsibilities:
- Seeking an innovative and experienced cell and molecular biologist to investigate the role of DNA damage repair pathways in cell cycle control.
- The focus of the work will be the characterization of biomarkers associated with sensitivity to DNA damage repair checkpoint inhibitors in human tumor cell lines.
- One of the goals is to identify and implement functional assays to assess DNA repair deficiency in human tumor cells using immunofluorescence microscopy and western blotting.
- Another goal is to characterize the effects of DNA damage repair checkpoint inhibitors and chemotherapy on cell cycle progression, using both synchronized and unsynchronized cell populations.
- Finally, we are planning to implement small molecule inhibitor screens using DNA repair and cell cycle effects as readouts.
- The laboratory has access to state-of-the art flow cytometry, microscopy, molecular and cellular tools and methodologies.
- The successful candidate will work in collaboration with an experienced team of molecular/cell biologists and in-house facilities providing technical support.
Summary of Qualifications:
- Candidate should possess a PhD in molecular/cell biology, preferably with an emphasis on DNA repair and cell cycle control as part of their PhD. OR PhD in biochemistry, molecular/cell biology or related discipline with at least 2 years of biochemical and molecular/cell biology experience.
- Candidates with a MS will also be considered but only if they have 6+ years of biochemical and molecular/cell biology experience.
- Expertise in signaling pathways and kinase biology would be a great advantage.
- Extensive cell biology experience and a broad knowledge base and expertise in flow cytometry cell cycle analysis and/or fluorescence imaging and microscopy is strongly preferred.
- Background in breast or ovarian cancer research is a plus.
- Qualified candidates must demonstrate a strong work ethic, attention to detail, a collaborative spirit and a consistent record of achievement, as evidenced by previous work and letters of reference.
- They must also be enthusiastic for science and discovery and show self-discipline and the ability to work independently as well as part of a group.