Research Associate - Process Development Unit

South San Francisco, CA 94080

Posted: 01/17/2019 Employment Type: Contract-to-Hire Industry: Clinical & Scientific Job Number: 14656

South San Francisco, CA



Our client is an exciting new company with laboratories in the San Francisco Bay Area that is developing T cell therapies for the eradication of solid tumors. The identification of neo-epitopes that serve as private mutations for each patient’ s cancer creates a unique opportunity to engineer autologous T cells that target and kill tumors expressing these neo-antigens.  The unique T-cell receptor (TCR) sequences obtained from these neoepitope-reactive cells are then engineered into T cells from the patient’ s own blood to produce therapeutic product: a tsunami of fresh, active T cells that, following infusion into the patient, recognize and attack each patient’ s cancer cells.

Research Associate - Process Development Unit

The candidate will work with the team for the process development of manufacturing for engineered T cells. He/she will interact closely with scientists and other research associates to transfer the technology from small scale research to large scale processes.  The ideal candidate will have experience in working with primary human T cells. She/he will be actively performing experiments and should be highly proficient in state of the art techniques for cell culture. The candidate should enjoy operating in an exceptionally dynamic and cooperative environment.

  • The Research Associate will perform PBMC isolation, cell separation and subset enrichment, cell expansion, formulation and cryopreservation.
  • The candidate will perform cell-based assays.
  • This individual will complete cell analysis using flow cytometry.

Minimum qualifications:
  • The ideal candidate should hold a Bachelor’ s degree with 3+ years’ experience, or hold a Master’ s degree with 2+ year experience in Cell Biology or related field
  • The candidate should be highly goal-driven and have demonstrated the ability to focus on time-sensitive objectives.
  • She/he must have excellent organizational skills and should be able to communicate clearly and concisely, both verbally and in the form of written reports.
  • Must have experience in sterile cell culture.
  • Proficiency with basic flow cytometry is a must.
  • Proven ability to work independently, as well as to collaborate with peers and work effectively in a fast-paced team-oriented environment.

Jesse Ashworth

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