Chromatography Associate Scientist, Assay Development

Redwood City, CA 94063

Posted: 01/13/2020 Employment Type: Direct Hire Industry: Clinical & Scientific Job Number: 16966

Job Description



Job Description

Chromatography Associate Scientist, Assay Development

Position Summary

We are looking for an Associate Scientist with knowledge of chromatography to join our team in our {location} office. This position reports to a Scientist/Team Leader.  This person will be working with Assay Development, QC, and Process Development.  This role is responsible for developing, qualifying, transferring, and troubleshooting chromatography-based assays in support of product characterization/release and bioanalysis.

What You’ ll Do
  • Work with senior scientific personnel to design, develop, qualify, troubleshoot, and transfer chromatography-based assays to internal and external scientists.
  • Apply separation sciences to the characterization of proteins, particle size, and higher-order protein structure, and in support of plate and enzyme-based assays.
  • Participate in decisions on experimental approaches and interpretation of data.
  • Work collaboratively with different research and development departments to evaluate and implement new assay formats and/or technologies.
  • Perform internal sample analysis as needed in support of product characterization and preclinical studies.
  • Transfer assays to and oversee work at Contract Research Organizations and in the QC group.
  • Maintain current knowledge of regulatory requirements for bioanalytical and product characterization assays
  • Write test procedures, documented standard test methods, SOPs, protocols, and technical reports.
  • Present project status updates in internal and external forums.
  • Maintain excellent documentation of laboratory activities.
  • Perform routine lab maintenance.
  • Other responsibilities may be assigned as needed

About You
  • Minimum of a biological science or similar Bachelor’ s degree with 4-5 years’ experience in a biotech company, or a Master’ s degree with 2-3 years’ experience, or an equivalent combination of education and experience
  • Experience in assay development is required
  • Ability to read and extract information from published literature and internal reports is required.
  • Expertise is required in HPLC and CE methods such as reversed-phased HPLC, size-exclusion HPLC, ion-exchange HPLC, affinity HPLC, CE-SDS, FFF-MALS, UPLC, and cIEF). Knowledge of Chemstation software is required.
  • Knowledge of LCMS is strongly desired
  • Experience in the qualification/validation of quantitative assays and knowledge of FDA requirements is strongly desired.
  • Broad knowledge of protein, cell, or nucleic acid assay methods and biochemistry with application to gene therapy is strongly desired.
  • Background in the area of retinal or genetic diseases is desired, with an understanding of AAV biology a plus.
  • Must be a self-starter, proactive, co-operative, and proficient at working both independently and in a small team environment.
  • Proven initiative and demonstrated accountability in a fast-paced environment with high degree of flexibility.
  • Detail oriented and with time management skills
  • Excellent verbal and written communication skills.
  • Experience in presenting data through written reports and oral presentation; publication in a peer-reviewed journal or presentation at a conference is desired.
  • Proficiency with SoftMaxPro, GraphPad Prism, JMP and other common analytical software desired.
  • Proficient with MS Office and other common office software.







Meet Your Recruiter

Ron Tess

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